Several platforms/technologies are available among the NPRC laboratories encompassing traditional to state-of-the-art methodologies. These include radiommunoassays (RIA) working with both alpha and beta particles, enzyme-linked immunoabsorbent assays (ELISA), chromatography separations, automated clinical platforms, high performance liquid chromatography (HPLC) linked with UV or electrochemical detection, and tandem tiple quadrupole mass spectrometry (LC/MS/MS).